News | October 30, 2000

Universal gene expression software is being offered as freeware

Rosetta Inpharmatics' GEML Conductor tools can be downloaded free of charge

Version 1.0 of Rosetta Inpharmatics' Gene Expression Markup Language (GEML) Conductor tools is now available for downloading from the company website (http://www.rii.com.). This suite of applications, which employs an open-standard XML file format, enables researchers to visualize and exchange data between different gene expression databases and analysis systems.

The company refers to its GEML Conductor tool as a universal solution for visualizing and exchanging gene expression information produced by different technology platforms. It allows users to convert any well-formatted gene expression data file into a common, flexible data format.

Rosetta GEML Conductor tools' features include:

  • File Conversion. Users can convert any gene expression data file, including Affymetrix GeneChip and BioDiscovery AutoGen, into the GEML format.
  • Plot Viewer. Users can visualize and share data by turning any GEML profile into a plot. The Plot Viewer includes a Zoom feature, which allows magnification into or out of particular sections of a plot.
  • Magic Lasso. Users can select specific plot areas for closer viewing.
  • Intensity Plot Viewer. Users can measure the intensity of one channel of data against the intensity of another channel of data.
  • Customizable Visualization. Users can customize groups, colors, and labels according to viewer preferences.
  • InstaLink. Users can access built-in hotlinks to popular databases and information centers on the World Wide Web.
  • Table Viewer. Users can convert GEML data into customizable tables with resizable and reorderable columns.

"The inability to analyze gene expression data from multiple technology platforms has long been hampered by software compatibility issues," stated Mark Boguski, senior vice president of research and development for Rosetta Inpharmatics. "By translating diverse data formats into a single common format, the Rosetta GEML Conductor tools enable users to share and visualize information across platforms, thus maximizing the value of gene expression data. The use of GEML will support information flow across a variety of laboratory settings. This is consistent with Rosetta Inpharmatics' long-term goal of supporting its partners in advancing genomics research and expediting discovery."

About the GEML (Gene Expression Markup Language) file format
The GEML file format facilitates the interchange of data from DNA chip and other gene expression technologies into a consistent format for more efficient and extensive data analysis. GEML was developed by Rosetta Inpharmatics in an effort to accommodate the increasing market need for researchers to have a consistent gene expression data format to use in analyzing data from the growing number of available gene expression technologies.

About Rosetta Inpharmatics
Rosetta Inpharmatics offers informational genomics solutions through its proprietary platform that accelerates and enhances the drug discovery process for pharmaceutical and biotechnology companies. Rosetta Inpharmatics' approach converts the rapidly growing amount of gene expression data, into organized, statistically driven, information-based results.

Rosetta Inpharmatics provides a proprietary gene expression profiling platform, consisting of hardware and software products, that uses gene expression profiles to provide seamless solutions for efficient, cost- effective and powerful discovery programs. Rosetta Inpharmatics' technology builds a critical mass of coherent gene expression data collected from DNA microarrays, which are comprised of DNA fragments attached to glass slides in a grid-like pattern. This platform provides comprehensive, simultaneous descriptions of a compound's effect on all relevant targets within a cell.

For more information, contact Mary C. Drummond, senior director of marketing for Rosetta Inpharmatics Inc., at 425-823-7369 or mdrummond@rii.com.

For more information on Rosetta Inpharmatics and its tools, check out these related articles:

MicroArrays Take on Signal Tranduction

Expression microarrays score twice


Edited by Laura DeFrancesco
Managing Editor, Bioresearch Online
Email: ldefrancesco@bioresearchonline.com

Source: Rosetta Inpharmatics